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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0011860,
umls-concept:C0021655,
umls-concept:C0026882,
umls-concept:C0032659,
umls-concept:C0039082,
umls-concept:C0220908,
umls-concept:C0311400,
umls-concept:C0599883,
umls-concept:C1335671,
umls-concept:C1955918,
umls-concept:C2603343
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-6
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pubmed:abstractText |
Adiponectin is an adipokine with insulin-sensitising and anti-atherogenic properties. Several reports suggest that genetic variants in the adiponectin gene are associated with circulating levels of adiponectin, insulin sensitivity and type 2 diabetes risk. Recently two receptors for adiponectin have been cloned. Genetic studies have yielded conflicting results on the role of these genes and type 2 diabetes predisposition. In this study we aimed to evaluate the potential role of genetic variation in these genes in syndromes of severe insulin resistance, type 2 diabetes and in related metabolic traits in UK Europid populations.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-10466767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-10547847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-10622252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-11222466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-11479627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-11479628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-11812766,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-12086965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-12354786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-12368907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-12802337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-14551916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-14693662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15105989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15210937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15277397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15504979,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15855354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15918014,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-15983228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-16205883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-16443913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-16505255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-16622416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-16724230,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17216283-7712700
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0012-186X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
555-62
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17216283-Diabetes Mellitus, Type 2,
pubmed-meshheading:17216283-Exons,
pubmed-meshheading:17216283-Genetic Predisposition to Disease,
pubmed-meshheading:17216283-Genotype,
pubmed-meshheading:17216283-Great Britain,
pubmed-meshheading:17216283-Humans,
pubmed-meshheading:17216283-Insulin Resistance,
pubmed-meshheading:17216283-Mutation,
pubmed-meshheading:17216283-Polymerase Chain Reaction,
pubmed-meshheading:17216283-Polymorphism, Single Nucleotide,
pubmed-meshheading:17216283-Receptors, Adiponectin,
pubmed-meshheading:17216283-Receptors, Cell Surface,
pubmed-meshheading:17216283-Risk Assessment
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pubmed:year |
2007
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pubmed:articleTitle |
Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.
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pubmed:affiliation |
Metabolic Disease Group, The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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