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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0018787,
umls-concept:C0035015,
umls-concept:C0178539,
umls-concept:C0205263,
umls-concept:C0220905,
umls-concept:C0332206,
umls-concept:C0520484,
umls-concept:C1548437,
umls-concept:C1801960,
umls-concept:C1882923,
umls-concept:C2587213
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-11
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pubmed:abstractText |
In heart allograft in the rat, a sustained costimulation blockade with CTLA4Ig prevents alloreactive T-cell activation and promotes a long-term graft survival through the action of tolerogeneic dendritic cells. It is unclear whether similar mechanisms might occur after xenotransplantation. To test that hypothesis, we have analyzed the action of CTLA4Ig in a model of CD4(+)T cell-mediated xenograft rejection.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0908-665X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-33
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pubmed:meshHeading |
pubmed-meshheading:17214702-Adenoviridae,
pubmed-meshheading:17214702-Animals,
pubmed-meshheading:17214702-Antigens, CD28,
pubmed-meshheading:17214702-Antigens, CD80,
pubmed-meshheading:17214702-Cardiovascular Diseases,
pubmed-meshheading:17214702-Cells, Cultured,
pubmed-meshheading:17214702-Cricetinae,
pubmed-meshheading:17214702-Cyclosporine,
pubmed-meshheading:17214702-Graft Rejection,
pubmed-meshheading:17214702-Graft Survival,
pubmed-meshheading:17214702-Heart Transplantation,
pubmed-meshheading:17214702-Immunoconjugates,
pubmed-meshheading:17214702-Male,
pubmed-meshheading:17214702-Rats,
pubmed-meshheading:17214702-Spleen,
pubmed-meshheading:17214702-T-Lymphocytes, Regulatory,
pubmed-meshheading:17214702-Transplantation, Heterologous
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pubmed:year |
2007
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pubmed:articleTitle |
Induction of regulatory cells and control of cellular but not vascular rejection by costimulation blockade in hamster-to-rat heart xenotransplantation.
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pubmed:affiliation |
INSERM U643, Nantes, ITERT, Nantes, Univ Nantes, UFR of Medicine, Nantes, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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