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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-11
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pubmed:abstractText |
It has been established that periodontal diseases are more prevalent and of greater severity in diabetic patients than in nondiabetic patients. Recent studies have underscored the role of monocytes and macrophages in periodontal tissue inflammation and destruction in diabetic patients. Although it has been shown that monocytes isolated from diabetic patients produce more inflammatory cytokines and that gingival crevicular fluid collected from diabetic patients contains higher levels of inflammatory cytokines than that obtained from nondiabetic patients, the underlying mechanisms are not well understood.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Fenofibrate,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Hypolipidemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxisome Proliferator-Activated...,
http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazolidinediones,
http://linkedlifedata.com/resource/pubmed/chemical/pioglitazone
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-3484
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17214637-Chemokines,
pubmed-meshheading:17214637-Cytokines,
pubmed-meshheading:17214637-Fenofibrate,
pubmed-meshheading:17214637-Glucose,
pubmed-meshheading:17214637-Histiocytes,
pubmed-meshheading:17214637-Humans,
pubmed-meshheading:17214637-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:17214637-Hypoglycemic Agents,
pubmed-meshheading:17214637-Hypolipidemic Agents,
pubmed-meshheading:17214637-Inflammation Mediators,
pubmed-meshheading:17214637-Lipopolysaccharides,
pubmed-meshheading:17214637-Nitric Oxide,
pubmed-meshheading:17214637-Nitric Oxide Synthase Type II,
pubmed-meshheading:17214637-Peroxisome Proliferator-Activated Receptors,
pubmed-meshheading:17214637-Simvastatin,
pubmed-meshheading:17214637-Thiazolidinediones,
pubmed-meshheading:17214637-Time Factors,
pubmed-meshheading:17214637-U937 Cells
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pubmed:year |
2007
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pubmed:articleTitle |
High glucose-boosted inflammatory responses to lipopolysaccharide are suppressed by statin.
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pubmed:affiliation |
Division of Endocrinology, Diabetes and Medical Genetics, Department of Medicine, Medical University of South Carolina, Charleston, SC 29403, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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