Source:http://linkedlifedata.com/resource/pubmed/id/17214359
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6C
|
| pubmed:dateCreated |
2007-1-11
|
| pubmed:abstractText |
Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal length and stability thus leading to cellular immortalisation. hTERT (human telomerase reverse transcriptase) gene is the rate-limiting determinant of telomerase reactivation. The present study aims to quantitatively measure the expression of hTERT mRNA in human breast cancer, examine the association between hTERT and the clinicopathological characteristics of the cancer specimens including the Nottingham Prognostic Index (NPI) and to explore the relationship between hTERT expression and clinical outcome.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0250-7005
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
4901-4
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| pubmed:meshHeading |
pubmed-meshheading:17214359-Breast Neoplasms,
pubmed-meshheading:17214359-Disease-Free Survival,
pubmed-meshheading:17214359-Humans,
pubmed-meshheading:17214359-Neoplasm Staging,
pubmed-meshheading:17214359-RNA, Messenger,
pubmed-meshheading:17214359-Telomerase,
pubmed-meshheading:17214359-Treatment Outcome
|
| pubmed:articleTitle |
hTERT mRNA expression is associated with a poor clinical outcome in human breast cancer.
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| pubmed:affiliation |
St. George's, University of London, UK.
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| pubmed:publicationType |
Journal Article
|