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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-1-23
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pubmed:abstractText |
This paper presents morphological (light- and electron-microscopical) evidence for the role of the mesonephros in contributing cells to the differentiating indifferent gonad and, after sexual differentiation, to the testis. A continuous process is revealed during which segregation of cells occurs from the developing and regressing mesonephros. Additionally, the complementary role of the coelomic epithelium in gonadal ridge and testis formation is demonstrated. The differentiation of testicular cords, their remodelling from a primary reticulum, and the composition and further change of the cellular content during the period after sexual differentiation is described using a computer-aided three-dimensional reconstruction system. Apart from these morphogenetic events, cytodifferentiation in the somatic cells of the indifferent gonad and of the early differentiated testis is demonstrated using indirect immunofluorescence in combination with monoclonal antibodies to the intermediate filament proteins keratin 8 and 18 and vimentin. The immunohistochemical results show that different forms of cytodifferentiation coexist among the somatic cells present in the indifferent gonad and in the testis early after sexual differentiation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0741-0581
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-57
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1721087-Animals,
pubmed-meshheading:1721087-Antibodies, Monoclonal,
pubmed-meshheading:1721087-Cell Differentiation,
pubmed-meshheading:1721087-Fluorescent Antibody Technique,
pubmed-meshheading:1721087-Image Processing, Computer-Assisted,
pubmed-meshheading:1721087-Keratins,
pubmed-meshheading:1721087-Male,
pubmed-meshheading:1721087-Mesonephros,
pubmed-meshheading:1721087-Rabbits,
pubmed-meshheading:1721087-Sertoli Cells,
pubmed-meshheading:1721087-Spermatic Cord,
pubmed-meshheading:1721087-Testis,
pubmed-meshheading:1721087-Vimentin
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pubmed:year |
1991
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pubmed:articleTitle |
Fine structural characteristics of testicular cord formation in the developing rabbit gonad.
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pubmed:affiliation |
Anatomical Institute, University of Bonn, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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