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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-8
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pubmed:abstractText |
Class switching from IgM/IgG/IgA to IgE is required for B cells to express IgE. This requires class switch recombination in the Ig heavy-chain gene locus. It is generally believed that class switch recombination occurs in lymphoid tissue, but it was recently shown that class switching to IgE occurs in the nasal mucosa in allergic rhinitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0091-6749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-8
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pubmed:dateRevised |
2008-12-15
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pubmed:meshHeading |
pubmed-meshheading:17208604-Adult,
pubmed-meshheading:17208604-Asthma,
pubmed-meshheading:17208604-Bronchi,
pubmed-meshheading:17208604-Cytidine Deaminase,
pubmed-meshheading:17208604-Female,
pubmed-meshheading:17208604-Humans,
pubmed-meshheading:17208604-Hypersensitivity, Immediate,
pubmed-meshheading:17208604-Immunoglobulin Class Switching,
pubmed-meshheading:17208604-Immunoglobulin E,
pubmed-meshheading:17208604-Immunoglobulin epsilon-Chains,
pubmed-meshheading:17208604-Male,
pubmed-meshheading:17208604-Middle Aged,
pubmed-meshheading:17208604-RNA, Messenger,
pubmed-meshheading:17208604-Recombination, Genetic,
pubmed-meshheading:17208604-Respiratory Mucosa
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pubmed:year |
2007
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pubmed:articleTitle |
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma.
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pubmed:affiliation |
Randall Division of Cell and Molecular Biophysics, King's College London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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