Source:http://linkedlifedata.com/resource/pubmed/id/17205531
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2007-2-5
|
| pubmed:abstractText |
The role of coffee in the aetiology of hepatocellular carcinoma has raised great interest. In Italy, coffee consumption is high, thus allowing the investigation of the topic over a broad range of consumption. A hospital-based case-control study was conducted in Italy in 1999-2002, including 185 incidents, histologically confirmed cases of hepatocellular carcinoma aged 43-84 years. Controls were 412 subjects admitted to the same hospitals' networks for acute, non-neoplastic diseases unrelated to diet. Coffee and tea consumption were assessed using a validated food-frequency questionnaire. Odds ratios (ORs) and corresponding the 95% confidence intervals (CI) were computed using unconditional multiple logistic regression, adjusting for hepatitis viruses seropositivity, alcohol intake, smoking habits and other potential confounding factors. Compared to people who drunk <14 cups/week of coffee, the risk of hepatocellular carcinoma decreased for increasing levels of consumption (OR=0.4, 95% CI: 0.2-1.1 for >or=28 cups/week, p for trend = 0.02). In the present study, inverse relations were observed across strata of hepatitis C and, B virus infections and alcohol drinking. No significant association emerged with consumption of decaffeinated coffee (OR=0.7, 95% CI=0.2-2.5) or tea (OR=1.4, 95% CI=0.8-2.7). The present study supports the hypothesis of a favourable effect of coffee, though not decaffeinated coffee and tea, on the risk on hepatocellular carcinoma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0020-7136
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| pubmed:author |
pubmed-author:CasarinPietroP,
pubmed-author:CrispoAnnaA,
pubmed-author:CrovattoMarinaM,
pubmed-author:Dal MasoLuiginoL,
pubmed-author:FranceschiSilviaS,
pubmed-author:IzzoFrancescoF,
pubmed-author:La VecchiaCarloC,
pubmed-author:MontellaMaurizioM,
pubmed-author:PoleselJerryJ,
pubmed-author:TalaminiRenatoR,
pubmed-author:TommasiLuigi GabrieleLG
|
| pubmed:copyrightInfo |
(c) 2006 Wiley-Liss, Inc.
|
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
120
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1555-9
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| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:17205531-Adult,
pubmed-meshheading:17205531-Aged,
pubmed-meshheading:17205531-Aged, 80 and over,
pubmed-meshheading:17205531-Carcinoma, Hepatocellular,
pubmed-meshheading:17205531-Case-Control Studies,
pubmed-meshheading:17205531-Coffee,
pubmed-meshheading:17205531-Female,
pubmed-meshheading:17205531-Hepacivirus,
pubmed-meshheading:17205531-Hepatitis B, Chronic,
pubmed-meshheading:17205531-Hepatitis B virus,
pubmed-meshheading:17205531-Hepatitis C, Chronic,
pubmed-meshheading:17205531-Humans,
pubmed-meshheading:17205531-Incidence,
pubmed-meshheading:17205531-Italy,
pubmed-meshheading:17205531-Liver Neoplasms,
pubmed-meshheading:17205531-Lymphoma,
pubmed-meshheading:17205531-Male,
pubmed-meshheading:17205531-Middle Aged,
pubmed-meshheading:17205531-Odds Ratio,
pubmed-meshheading:17205531-Questionnaires,
pubmed-meshheading:17205531-Risk Factors,
pubmed-meshheading:17205531-Tea
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Coffee and tea consumption and risk of hepatocellular carcinoma in Italy.
|
| pubmed:affiliation |
Servizio di Epidemiologia, Istituto Tumori Fondazione Pascale, Naples, Italy.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|