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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1976-2-2
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pubmed:abstractText |
In the completed adjuvant chemotherapy lung trials conducted by the Veterans Administration Surgical Group, the cell type was recorded in 2,341 of 2,349 curative resections; extent of lymph node involvement was known in all cases. Nodes were normal in 1,231 patients. Five- and ten-year survival computed by the life-table method was 33.7% and 20.4%, respectively. These rates were significantly greater than the 16.2% and 8.8% recorded in 1,118 patients whose nodes showed metastases. Among patients whose cell type was known, five-year survival in 484 with hilar node involvement was 17.4% and was not significantly different from 20.1% in 364 patients in whom only lobar nodes were involved. The survival was 8.9% in 268 patients with cancer in the mediastinal nodes; this was significantly worse than either of the aforementioned groups. A five-year survival of 26.8% in 1,482 patients with squamous cell carcinoma was greater than the 24.3% in 359 with adenocarcinoma and 22.4% in 500 with undifferentiated cell types, but the differences were not significant. Variations between these groups remained nonsignificant when nodes were normal and were of only borderline significance, at the 5% level, when they showed metastasis. When a curative resection has been accomplished, cell-type as classified in this study has little bearing on long-term survival, whereas the presence of node metastasis as well as its location is of the utmost importance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-4975
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
501-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:172035-Adenocarcinoma,
pubmed-meshheading:172035-Adult,
pubmed-meshheading:172035-Aged,
pubmed-meshheading:172035-Bronchial Neoplasms,
pubmed-meshheading:172035-Carcinoma, Small Cell,
pubmed-meshheading:172035-Carcinoma, Squamous Cell,
pubmed-meshheading:172035-Cyclophosphamide,
pubmed-meshheading:172035-Humans,
pubmed-meshheading:172035-Lung Neoplasms,
pubmed-meshheading:172035-Lymphatic Metastasis,
pubmed-meshheading:172035-Mechlorethamine,
pubmed-meshheading:172035-Middle Aged,
pubmed-meshheading:172035-Prognosis,
pubmed-meshheading:172035-Time Factors
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pubmed:year |
1975
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pubmed:articleTitle |
Relationship of cell type and lymph node metastasis to survival after resection of bronchial carcinoma.
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pubmed:publicationType |
Journal Article
|