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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-7-4
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pubmed:abstractText |
Delirium frequently occurs in the context of infection and other inflammatory conditions associated with elevated levels of cytokines. Cytokines used therapeutically can induce symptoms of delirium as an adverse effect. We hypothesized that a causal relationship might exist between delirium and cytokine production during illness. Further, we speculated that the APOE genotype of patients might influence their rate of recovery from delirium given that APOE is associated with amyloid deposition, increased susceptibility to exogenous neurotoxins, and can affect the immune response.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0885-6230
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
688-94
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17203511-APACHE,
pubmed-meshheading:17203511-Acute Disease,
pubmed-meshheading:17203511-Aged,
pubmed-meshheading:17203511-Aged, 80 and over,
pubmed-meshheading:17203511-Alleles,
pubmed-meshheading:17203511-Alzheimer Disease,
pubmed-meshheading:17203511-Apolipoprotein E4,
pubmed-meshheading:17203511-Apolipoproteins E,
pubmed-meshheading:17203511-Cross-Sectional Studies,
pubmed-meshheading:17203511-Cytokines,
pubmed-meshheading:17203511-Delirium,
pubmed-meshheading:17203511-Disability Evaluation,
pubmed-meshheading:17203511-Female,
pubmed-meshheading:17203511-Genetic Markers,
pubmed-meshheading:17203511-Genotype,
pubmed-meshheading:17203511-Hospitalization,
pubmed-meshheading:17203511-Humans,
pubmed-meshheading:17203511-Insulin-Like Growth Factor I,
pubmed-meshheading:17203511-Interferon-gamma,
pubmed-meshheading:17203511-Male,
pubmed-meshheading:17203511-Mental Status Schedule,
pubmed-meshheading:17203511-Prognosis,
pubmed-meshheading:17203511-Recurrence,
pubmed-meshheading:17203511-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
APOE and cytokines as biological markers for recovery of prevalent delirium in elderly medical inpatients.
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pubmed:affiliation |
Department of Ageing and Health, Guy's and St Thomas' NHS Foundation Trust, London. dimaadamis@yahoo.com
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pubmed:publicationType |
Journal Article
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