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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-4
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pubmed:abstractText |
In animal models, the adipocyte-secreted hormone leptin increases energy expenditure by increasing sympathetic outflow but its role in humans remains to be elucidated. We evaluated whether inducing hypoleptinaemia (with and without administration of leptin at replacement doses) for 3 days would influence catecholamine levels and sympathetic and parasympathetic activity in healthy humans.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0300-0664
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-57
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17201801-Adult,
pubmed-meshheading:17201801-Autonomic Nervous System,
pubmed-meshheading:17201801-Catecholamines,
pubmed-meshheading:17201801-Creatinine,
pubmed-meshheading:17201801-Dopamine,
pubmed-meshheading:17201801-Double-Blind Method,
pubmed-meshheading:17201801-Epinephrine,
pubmed-meshheading:17201801-Fasting,
pubmed-meshheading:17201801-Female,
pubmed-meshheading:17201801-Heart Rate,
pubmed-meshheading:17201801-Humans,
pubmed-meshheading:17201801-Leptin,
pubmed-meshheading:17201801-Norepinephrine,
pubmed-meshheading:17201801-Signal Processing, Computer-Assisted,
pubmed-meshheading:17201801-Sodium,
pubmed-meshheading:17201801-Statistics, Nonparametric
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pubmed:year |
2007
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pubmed:articleTitle |
Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans.
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pubmed:affiliation |
Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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