Source:http://linkedlifedata.com/resource/pubmed/id/17199921
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2007-1-3
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pubmed:abstractText |
Severe preeclampsia, and hemolysis, elevated liver enzymes, and low platelet syndrome (HELLP) are serious complications of pregnancy, and evidence suggests a genetic basis for these conditions. A G1528C mutation in the alpha-subunit of the mitochondrial trifunctional protein (MTP) gene has been identified in association with these conditions. The aim of this study is to explore the carrier rate of the G1528C mutation in the MTP gene in pregnant women with severe preeclampsia, HELLP syndrome and in their newborns, as well as in a normal pregnant population, so as to determine its association with maternal liver disease among women in Beijing.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0529-567X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
672-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17199921-Case-Control Studies,
pubmed-meshheading:17199921-China,
pubmed-meshheading:17199921-Female,
pubmed-meshheading:17199921-Fetal Blood,
pubmed-meshheading:17199921-Fetal Diseases,
pubmed-meshheading:17199921-Genetic Testing,
pubmed-meshheading:17199921-HELLP Syndrome,
pubmed-meshheading:17199921-Humans,
pubmed-meshheading:17199921-Infant, Newborn,
pubmed-meshheading:17199921-Multienzyme Complexes,
pubmed-meshheading:17199921-Point Mutation,
pubmed-meshheading:17199921-Polymerase Chain Reaction,
pubmed-meshheading:17199921-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17199921-Pre-Eclampsia,
pubmed-meshheading:17199921-Pregnancy,
pubmed-meshheading:17199921-Prospective Studies,
pubmed-meshheading:17199921-Risk Assessment
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pubmed:year |
2006
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pubmed:articleTitle |
[Screening for G1528C mutation in mitochondrial trifunctional protein gene in pregnant women with severe preeclampsia and new born infant].
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100083, China.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't,
Multicenter Study
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