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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-3
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pubmed:abstractText |
Conjugated linoleic acid (CLA) is a natural constituent of dairy products, specific isomers of which have recently been found to have insulin sensitizing and possible antiobesity actions. Chromium is a micronutrient which, as the picolinate (CrP), has been shown to increase insulin sensitivity in animal models, including the JCR:LA-cp rat. We tested the hypothesis that these agents may have beneficial synergistic effects on the micro- and macrovasculopathy associated with hyperinsulinaemia and early type 2 diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1462-8902
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-95
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17199723-Adiponectin,
pubmed-meshheading:17199723-Albuminuria,
pubmed-meshheading:17199723-Animals,
pubmed-meshheading:17199723-Aorta,
pubmed-meshheading:17199723-Body Weight,
pubmed-meshheading:17199723-Diabetic Nephropathies,
pubmed-meshheading:17199723-Dose-Response Relationship, Drug,
pubmed-meshheading:17199723-Drug Synergism,
pubmed-meshheading:17199723-Eating,
pubmed-meshheading:17199723-Insulin,
pubmed-meshheading:17199723-Insulin Resistance,
pubmed-meshheading:17199723-Kidney,
pubmed-meshheading:17199723-Linoleic Acids, Conjugated,
pubmed-meshheading:17199723-Male,
pubmed-meshheading:17199723-Metabolic Syndrome X,
pubmed-meshheading:17199723-Picolinic Acids,
pubmed-meshheading:17199723-Rats,
pubmed-meshheading:17199723-Tissue Culture Techniques,
pubmed-meshheading:17199723-Vasoconstriction
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pubmed:year |
2007
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pubmed:articleTitle |
Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.
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pubmed:affiliation |
Metabolic and Cardiovascular Diseases Laboratory, Alberta Institute for Human Nutrition, 4-10 Agriculture Forestry Centre, University of Alberta, Edmonton, AB, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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