rdf:type |
|
lifeskim:mentions |
umls-concept:C0003364,
umls-concept:C0205195,
umls-concept:C0205531,
umls-concept:C0216784,
umls-concept:C0226896,
umls-concept:C0442027,
umls-concept:C1120110,
umls-concept:C1527415,
umls-concept:C1704419,
umls-concept:C1960108,
umls-concept:C1999230
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-1-2
|
pubmed:abstractText |
By blocking the renin-angiotensin-aldosterone system (RAAS) at its rate-limiting step, renin inhibition may provide improved RAAS suppression. We investigated the blood pressure (BP)-lowering effects of the oral direct renin inhibitor aliskiren, alone or in combination with the angiotensin receptor blocker valsartan.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0895-7061
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
11-20
|
pubmed:dateRevised |
2009-2-24
|
pubmed:meshHeading |
pubmed-meshheading:17198906-Adult,
pubmed-meshheading:17198906-Aged,
pubmed-meshheading:17198906-Amides,
pubmed-meshheading:17198906-Antihypertensive Agents,
pubmed-meshheading:17198906-Blood Pressure,
pubmed-meshheading:17198906-Dose-Response Relationship, Drug,
pubmed-meshheading:17198906-Double-Blind Method,
pubmed-meshheading:17198906-Female,
pubmed-meshheading:17198906-Fumarates,
pubmed-meshheading:17198906-Humans,
pubmed-meshheading:17198906-Hydrochlorothiazide,
pubmed-meshheading:17198906-Hypertension,
pubmed-meshheading:17198906-Male,
pubmed-meshheading:17198906-Middle Aged,
pubmed-meshheading:17198906-Tetrazoles,
pubmed-meshheading:17198906-Valine
|
pubmed:year |
2007
|
pubmed:articleTitle |
Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan.
|
pubmed:affiliation |
Center for Experimental Therapeutics, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. jpool@bcm.tmc.edu
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|