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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0010031,
umls-concept:C0041904,
umls-concept:C0078058,
umls-concept:C0085109,
umls-concept:C0086418,
umls-concept:C0591833,
umls-concept:C1099354,
umls-concept:C1256770,
umls-concept:C1334043,
umls-concept:C1533157,
umls-concept:C1710548
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-1
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pubmed:abstractText |
To determine whether RNA interference (RNAi) could block hypoxia-induced upregulation of vascular endothelial growth factor (VEGF) in human corneal epithelial cells in vitro and inhibit and regress injury-induced murine corneal neovascularization in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0277-3740
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pubmed:author |
pubmed-author:AmbatiBalamurali KBK,
pubmed-author:AmbatiJayakrishnaJ,
pubmed-author:AminShivanS,
pubmed-author:DongZhengZ,
pubmed-author:HigginsEricE,
pubmed-author:JaniPoojaP,
pubmed-author:KaurRajwinderR,
pubmed-author:PatelAnupA,
pubmed-author:RichterElizabethE,
pubmed-author:SinghNirbhaiN,
pubmed-author:WildE AEA
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65-72
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pubmed:dateRevised |
2007-5-2
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pubmed:meshHeading |
pubmed-meshheading:17198016-Animals,
pubmed-meshheading:17198016-Anoxia,
pubmed-meshheading:17198016-Cell Culture Techniques,
pubmed-meshheading:17198016-Corneal Neovascularization,
pubmed-meshheading:17198016-Disease Models, Animal,
pubmed-meshheading:17198016-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17198016-Epithelium, Corneal,
pubmed-meshheading:17198016-Gene Silencing,
pubmed-meshheading:17198016-Gene Targeting,
pubmed-meshheading:17198016-Humans,
pubmed-meshheading:17198016-Leukocyte Count,
pubmed-meshheading:17198016-Luminescent Proteins,
pubmed-meshheading:17198016-Mice,
pubmed-meshheading:17198016-Plasmids,
pubmed-meshheading:17198016-RNA, Messenger,
pubmed-meshheading:17198016-RNA, Small Interfering,
pubmed-meshheading:17198016-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17198016-Transfection,
pubmed-meshheading:17198016-Up-Regulation,
pubmed-meshheading:17198016-Vascular Endothelial Growth Factor A
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pubmed:year |
2007
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pubmed:articleTitle |
Unique homologous siRNA blocks hypoxia-induced VEGF upregulation in human corneal cells and inhibits and regresses murine corneal neovascularization.
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pubmed:affiliation |
Department of Ophthalmology, Medical College of Georgia, Augusta, GA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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