Source:http://linkedlifedata.com/resource/pubmed/id/17197899
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-1-1
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pubmed:abstractText |
In the uterus, most alpha-fetoprotein (AFP) producing neoplasms belong to the categories of malignant mixed muellerian tumor, hepatoid carcinoma, and yolk sac tumor. We describe the case of a 44-year-old woman who presented with vaginal bleeding, pelvic mass, and preoperative elevated AFP serum level, clinically suggestive of a primary ovarian yolk sac tumor. However, histological examination revealed a uterine AFP-producing papillary serous carcinoma, which has metastasized to the ovaries. Upon review of the literature on primary endometrial neoplasms with AFP production, 2 categories with possibly different histogenesis and biological behavior become evident: the primary yolk sac tumor of the uterus in young patients (range, 24-49 years; mean, 34 years) and the common high grade endometrial carcinoma with yolk sac dedifferentiation or aberrant AFP production in elderly patients (range, 55-69 years; mean, 63.7 years). In addition to being only the second case of uterine AFP-producing papillary serous carcinoma, this case is unusual for its clinical and radiological presentation as well as the relatively young age of the patient.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0277-1691
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66-70
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pubmed:meshHeading |
pubmed-meshheading:17197899-Adult,
pubmed-meshheading:17197899-Endodermal Sinus Tumor,
pubmed-meshheading:17197899-Female,
pubmed-meshheading:17197899-Humans,
pubmed-meshheading:17197899-Molecular Mimicry,
pubmed-meshheading:17197899-Ovarian Neoplasms,
pubmed-meshheading:17197899-Tumor Markers, Biological,
pubmed-meshheading:17197899-Uterine Neoplasms,
pubmed-meshheading:17197899-alpha-Fetoproteins
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pubmed:year |
2007
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pubmed:articleTitle |
Alpha-fetoprotein-producing serous carcinoma of the uterus metastasizing to the ovaries, mimicking primary ovarian yolk sac tumor: a case report and review of the literature.
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pubmed:affiliation |
Department of Pathology, Florida Hospital Orlando, Orlando, Florida, USA. tranguyentienanh@hotmail.com
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pubmed:publicationType |
Journal Article,
Case Reports
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