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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-1
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pubmed:abstractText |
Exogenous thymosin beta-4 (Tbeta(4)) has been shown to inhibit the apoptosis in nontransformed human corneal epithelial cells that is triggered by ethanol. The purpose of this study is to examine whether exogenous Tbeta(4) protects SV40-immortalized human corneal epithelial T (HCE-T) cells against the toxic effects of Fas ligand (FasL) and hydrogen peroxide (H(2)O(2)) and to elucidate its mechanism of action.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-33
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pubmed:meshHeading |
pubmed-meshheading:17197512-Animals,
pubmed-meshheading:17197512-Apoptosis,
pubmed-meshheading:17197512-Blotting, Western,
pubmed-meshheading:17197512-Caspases,
pubmed-meshheading:17197512-Cell Culture Techniques,
pubmed-meshheading:17197512-Cell Line, Transformed,
pubmed-meshheading:17197512-Cytochalasin D,
pubmed-meshheading:17197512-Endocytosis,
pubmed-meshheading:17197512-Epithelium, Corneal,
pubmed-meshheading:17197512-Fas Ligand Protein,
pubmed-meshheading:17197512-Flow Cytometry,
pubmed-meshheading:17197512-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:17197512-Humans,
pubmed-meshheading:17197512-Hydrogen Peroxide,
pubmed-meshheading:17197512-Maximum Tolerated Dose,
pubmed-meshheading:17197512-Rabbits,
pubmed-meshheading:17197512-Recombinant Proteins,
pubmed-meshheading:17197512-Simian virus 40,
pubmed-meshheading:17197512-Tetrazolium Salts,
pubmed-meshheading:17197512-Thiazoles,
pubmed-meshheading:17197512-Thymosin
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pubmed:year |
2007
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pubmed:articleTitle |
Internalization is essential for the antiapoptotic effects of exogenous thymosin beta-4 on human corneal epithelial cells.
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pubmed:affiliation |
Institute of Biopharmaceutical Science, National Yang-Ming University, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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