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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-3
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pubmed:dateCreated |
2007-6-12
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pubmed:abstractText |
Reduced dopaminergic function may occur in depressive disorders. In this paper the results of two pilot studies examining different aspects of the dopamine system in depression are presented. First, the binding of [(11)C]FLB 457 to extrastriatal D(2) receptors was measured in a group of depressed patients. Second, the hypothesis that selective serotonin reuptake inhibiting (SSRI) antidepressants affect the striatal binding of [(11)C]raclopride was tested.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0165-0327
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-22
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pubmed:dateRevised |
2009-9-28
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pubmed:meshHeading |
pubmed-meshheading:17197036-Adult,
pubmed-meshheading:17197036-Brain,
pubmed-meshheading:17197036-Brain Mapping,
pubmed-meshheading:17197036-Carbon Radioisotopes,
pubmed-meshheading:17197036-Corpus Striatum,
pubmed-meshheading:17197036-Depressive Disorder, Major,
pubmed-meshheading:17197036-Dopamine Antagonists,
pubmed-meshheading:17197036-Female,
pubmed-meshheading:17197036-Humans,
pubmed-meshheading:17197036-Image Processing, Computer-Assisted,
pubmed-meshheading:17197036-Male,
pubmed-meshheading:17197036-Middle Aged,
pubmed-meshheading:17197036-Motivation,
pubmed-meshheading:17197036-Pilot Projects,
pubmed-meshheading:17197036-Positron-Emission Tomography,
pubmed-meshheading:17197036-Pyrrolidines,
pubmed-meshheading:17197036-Raclopride,
pubmed-meshheading:17197036-Radioligand Assay,
pubmed-meshheading:17197036-Receptors, Dopamine D2,
pubmed-meshheading:17197036-Reference Values,
pubmed-meshheading:17197036-Salicylamides,
pubmed-meshheading:17197036-Serotonin Uptake Inhibitors
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pubmed:year |
2007
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pubmed:articleTitle |
Extrastriatal D2 and striatal D2 receptors in depressive illness: pilot PET studies using [11C]FLB 457 and [11C]raclopride.
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pubmed:affiliation |
CSC-MRC Cyclotron Unit, Imperial College, Hammersmith Hospital, DuCane Rd., London, W12 0NN, UK. andrew.montgomery@ic.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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