Linked Life Data

17195422

Source:http://linkedlifedata.com/resource/pubmed/id/17195422

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-1-1
pubmed:abstractText
Minimal change disease (MCD) is a histopathological lesion in the kidney that is most commonly associated with nephrotic syndrome. The majority of the cases are idiopathic. Pathogenesis is not well understood, although T-cell-related mechanisms are implicated. Massive proteinuria leads to hypoalbuminemia, salt retention, disorder of hemostasis, hyperlipidemia and increased susceptibility to infections. Renal biopsy remains the gold standard for diagnosis. MCD is highly responsive to corticosteroids. Other immunosuppressive agents such as cyclophosphamide, cyclosporin, azathioprine and mycophenolate mofetil have been used to treat cases which are resistant to steroids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0038-4348
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1264-70
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Minimal change disease: a review.
pubmed:affiliation
Brody School of Medicine, East Carolina University, 2355 W. Arlington Boulevard, Greenville, North Carolina 37834, USA. sahat@ecu.edu
pubmed:publicationType
Journal Article, Review