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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-29
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pubmed:abstractText |
To generate a mouse model that can mimic human rheumatoid arthritis (RA). A major difference between RA in humans and collagen-induced arthritis (CIA) in mice is the lack of sex bias and autoantibodies in the animal model. We used DRB1*0401-transgenic mice to understand the role of DR4 in susceptibility and sex bias in RA.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-78
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17195209-Animals,
pubmed-meshheading:17195209-Arthritis, Experimental,
pubmed-meshheading:17195209-Arthritis, Rheumatoid,
pubmed-meshheading:17195209-Cytokines,
pubmed-meshheading:17195209-Female,
pubmed-meshheading:17195209-Flow Cytometry,
pubmed-meshheading:17195209-Genetic Predisposition to Disease,
pubmed-meshheading:17195209-HLA-DR4 Antigen,
pubmed-meshheading:17195209-Joints,
pubmed-meshheading:17195209-Male,
pubmed-meshheading:17195209-Mice,
pubmed-meshheading:17195209-Mice, Transgenic,
pubmed-meshheading:17195209-Sex Factors,
pubmed-meshheading:17195209-Spleen,
pubmed-meshheading:17195209-Thymus Gland
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pubmed:year |
2007
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pubmed:articleTitle |
New humanized HLA-DR4-transgenic mice that mimic the sex bias of rheumatoid arthritis.
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pubmed:affiliation |
Mayo Clinic, Rochester, Minnesota 55905, USA. taneja.veena@mayo.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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