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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2006-12-29
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pubmed:databankReference |
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pubmed:abstractText |
Genetic and biochemical studies have indicated an important role for lipid metabolism in human longevity. Ashkenazi Jewish centenarians and their offspring have large low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles as compared with control individuals. This profile also coincided with a lower prevalence of disease. Here, we investigate whether this observation can be confirmed for familial longevity in an outbred European population and whether it can be extended to sporadic longevity in the general population.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-11053677,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-11934219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-12060785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-12370215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-12507676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-12540621,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-12730251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-1450181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-14559957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-15166804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-15571545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-15714554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-15800976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-15888337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-16251894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-7252074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-8340104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-8961404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17194192-9050915
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1549-1676
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e495
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17194192-Aged,
pubmed-meshheading:17194192-Aged, 80 and over,
pubmed-meshheading:17194192-European Continental Ancestry Group,
pubmed-meshheading:17194192-Female,
pubmed-meshheading:17194192-Humans,
pubmed-meshheading:17194192-Lipoproteins,
pubmed-meshheading:17194192-Lipoproteins, HDL,
pubmed-meshheading:17194192-Lipoproteins, LDL,
pubmed-meshheading:17194192-Longevity,
pubmed-meshheading:17194192-Magnetic Resonance Spectroscopy,
pubmed-meshheading:17194192-Male,
pubmed-meshheading:17194192-Middle Aged,
pubmed-meshheading:17194192-Netherlands,
pubmed-meshheading:17194192-Particle Size
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pubmed:year |
2006
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pubmed:articleTitle |
Lipoprotein particle profiles mark familial and sporadic human longevity.
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pubmed:affiliation |
Department of Molecular Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands. b.t.heijmans@lumc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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