Source:http://linkedlifedata.com/resource/pubmed/id/17193331
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2006-12-28
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pubmed:abstractText |
Seven benzophenanthridine alkaloids, 1-7, were isolated from the roots of Zanthoxylum nitidum. Among them, two novel alkaloids, named (R)-8-[(R)-1-hydroxyethyl]dihydrochelerythrine (1) and 8-methoxynorchelerythrine (2), were structurally identified as new compounds on the basis of the spectroscopic analysis. Bioactivity evaluation showed that nitidine (3), dihydrochelerythrine (4), oxyavicine (5), 8-methoxychelerythrine (6), and 8-hydroxydihydrochelerythrine (7) exhibit comparable analgesic and anti-inflammatory effects as hydrocortisone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1612-1880
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
990-5
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pubmed:meshHeading |
pubmed-meshheading:17193331-Animals,
pubmed-meshheading:17193331-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:17193331-Benzophenanthridines,
pubmed-meshheading:17193331-Edema,
pubmed-meshheading:17193331-Male,
pubmed-meshheading:17193331-Mice,
pubmed-meshheading:17193331-Molecular Structure,
pubmed-meshheading:17193331-Pain,
pubmed-meshheading:17193331-Plant Roots,
pubmed-meshheading:17193331-Structure-Activity Relationship,
pubmed-meshheading:17193331-Zanthoxylum
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pubmed:year |
2006
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pubmed:articleTitle |
Benzophenanthridine alkaloids from Zanthoxylum nitidum (Roxb.) DC, and their analgesic and anti-inflammatory activities.
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pubmed:affiliation |
Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, P.R. China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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