Source:http://linkedlifedata.com/resource/pubmed/id/17191389
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-12-28
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pubmed:abstractText |
Antimicrobial resistance to the extended-spectrum cephalosporins is increasingly reported worldwide. In the local setting, nosocomial infections with multi-resistant Gram-negative bacilli are not uncommon and are a growing concern. However, there is limited data on the carriage rates of such organisms in the local setting. In May 2001, a prospective study was carried out to determine the enteric carriage rates of ceftazidime-resistant Gram negative bacilli (CAZ-R GNB) among residents of nursing homes and from in-patients of the geriatric and adult haematology wards of University Malaya Medical Centre. Ceftazidime-resistant Gram-negative bacilli (CAZ-R GNB) were detected in 25 samples (30%), out of which 6 were from nursing home residents, 5 from geriatric in-patients and 14 from the haematology unit. A total of 28 CAZ-R GNB were isolated and Escherichia coli (10) and Klebsiella pneumoniae (7) were the predominant organisms. Resistance to ceftazidime in E. coli and Klebsiella was mediated by extended-spectrum beta-lactamases (ESBLs). Although the majority of the CAZ-R GNB were from patients in the haematology ward, the six nursing home residents with CAZ-R GNB were enteric carriers of ESBL-producing coliforms. Prior exposure to antibiotics was associated with carriage of ESBL organisms and to a lesser extent, the presence of urinary catheters.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0126-8635
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-81
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pubmed:meshHeading |
pubmed-meshheading:17191389-Aged,
pubmed-meshheading:17191389-Anti-Bacterial Agents,
pubmed-meshheading:17191389-Ceftazidime,
pubmed-meshheading:17191389-Drug Resistance,
pubmed-meshheading:17191389-Enterobacteriaceae,
pubmed-meshheading:17191389-Enterobacteriaceae Infections,
pubmed-meshheading:17191389-Feces,
pubmed-meshheading:17191389-Hematologic Diseases,
pubmed-meshheading:17191389-Humans,
pubmed-meshheading:17191389-Inpatients,
pubmed-meshheading:17191389-Nursing Homes,
pubmed-meshheading:17191389-Polymerase Chain Reaction,
pubmed-meshheading:17191389-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:17191389-Prevalence,
pubmed-meshheading:17191389-beta-Lactam Resistance,
pubmed-meshheading:17191389-beta-Lactamases
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pubmed:year |
2005
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pubmed:articleTitle |
Faecal prevalence of extended-spectrum Beta-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients.
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pubmed:affiliation |
Departments of Medical Microbiology, University of Malaya.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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