Source:http://linkedlifedata.com/resource/pubmed/id/17189871
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2006-12-26
|
pubmed:abstractText |
Adiponectin [adipocyte C1q and collagen domain containing (ACDC)] is the most abundant adipose-specific protein. It is beneficial in that it improves insulin sensitivity and mitigates vascular damage, in addition to the possibility of it having anti-inflammatory properties. Clinical evidences demonstrate that serum adiponectin concentrations are increased in patients with type 1 diabetes (T1D) as well as in patients with microvascular complications. However, the genetic influence of the ACDC gene in T1D and diabetic microvascular complications is still unclear. The present study aims to evaluate the association of the ACDC genetic variation in T1D and diabetic nephropathy (DN).
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1056-8727
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
28-33
|
pubmed:meshHeading |
pubmed-meshheading:17189871-Adiponectin,
pubmed-meshheading:17189871-Adult,
pubmed-meshheading:17189871-DNA,
pubmed-meshheading:17189871-Diabetes Mellitus, Type 1,
pubmed-meshheading:17189871-Diabetic Nephropathies,
pubmed-meshheading:17189871-European Continental Ancestry Group,
pubmed-meshheading:17189871-Female,
pubmed-meshheading:17189871-Gene Amplification,
pubmed-meshheading:17189871-Humans,
pubmed-meshheading:17189871-Male,
pubmed-meshheading:17189871-Middle Aged,
pubmed-meshheading:17189871-Polymorphism, Genetic,
pubmed-meshheading:17189871-Polymorphism, Single Nucleotide,
pubmed-meshheading:17189871-Reference Values,
pubmed-meshheading:17189871-Sweden
|
pubmed:articleTitle |
Genetic association analysis of the adiponectin polymorphisms in type 1 diabetes with and without diabetic nephropathy.
|
pubmed:affiliation |
Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institute, SE-171 76 Stockholm, Sweden.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|