17189692

Source:http://linkedlifedata.com/resource/pubmed/id/17189692

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0243077, umls-concept:C0253457, umls-concept:C1527148
pubmed:issue	5
pubmed:dateCreated	2007-2-19
pubmed:abstractText	A new class of bicyclic pyrrolopyrimidine-based Janus kinase 3 (JAK-3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK-3.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinase 2, http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines, http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0960-894X
pubmed:author	pubmed-author:BooklandRoger GRG, pubmed-author:BrugelTodd ATA, pubmed-author:CabreraEd JEJ, pubmed-author:ChenJackJ, pubmed-author:ClarkMichael PMP, pubmed-author:DavisJan RJR, pubmed-author:DeBiswanathB, pubmed-author:EaswaranVijayV, pubmed-author:GeorgeKelly MKM, pubmed-author:GolebiowskiAdamA, pubmed-author:LaufersweilerMatthew JMJ, pubmed-author:LaughlinSteven KSK, pubmed-author:LeeWenlinW, pubmed-author:MaierJennifer AJA, pubmed-author:SabatMark PMP, pubmed-author:ThakurKumar DKD, pubmed-author:VanRensJohn CJC, pubmed-author:WebsterMark EME, pubmed-author:ZhangGeorgeG
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1250-3
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17189692-Autoimmune Diseases, pubmed-meshheading:17189692-Cell Line, Tumor, pubmed-meshheading:17189692-Cell Proliferation, pubmed-meshheading:17189692-Humans, pubmed-meshheading:17189692-Immunity, pubmed-meshheading:17189692-Janus Kinase 2, pubmed-meshheading:17189692-Janus Kinase 3, pubmed-meshheading:17189692-Pyrimidines, pubmed-meshheading:17189692-Pyrroles, pubmed-meshheading:17189692-Structure-Activity Relationship
pubmed:year	2007
pubmed:articleTitle	Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).
pubmed:affiliation	Procter and Gamble Pharmaceuticals, Health Care Research Center, 8700 Mason-Montgomery Road, Mason, OH 45040, USA. mclark@metastatix.com
pubmed:publicationType	Journal Article