Source:http://linkedlifedata.com/resource/pubmed/id/17187388
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2007-2-15
|
pubmed:abstractText |
Conflicting findings with regard to the teratogenic risks of first trimester use of paroxetine have prompted the FDA, Health Canada, and the manufacturer of the drug to issue warnings against its use during pregnancy. Given that untreated depression during pregnancy can lead to deleterious effect on the mother and her unborn fetus, data on the relationship between the dose and the range of malformations is warranted. This study attempts to quantify the association between first trimester exposure to paroxetine and congenital cardiac malformations, adjusting for possible confounders, and to quantify the dose-response relationship between paroxetine use and cardiac defects.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1542-9733
|
pubmed:author | |
pubmed:copyrightInfo |
(c) 2006 Wiley-Liss, Inc.
|
pubmed:issnType |
Print
|
pubmed:volume |
80
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
18-27
|
pubmed:meshHeading |
pubmed-meshheading:17187388-Abnormalities, Drug-Induced,
pubmed-meshheading:17187388-Adolescent,
pubmed-meshheading:17187388-Adult,
pubmed-meshheading:17187388-Antidepressive Agents, Second-Generation,
pubmed-meshheading:17187388-Dose-Response Relationship, Drug,
pubmed-meshheading:17187388-Female,
pubmed-meshheading:17187388-Heart Defects, Congenital,
pubmed-meshheading:17187388-Humans,
pubmed-meshheading:17187388-Middle Aged,
pubmed-meshheading:17187388-Paroxetine,
pubmed-meshheading:17187388-Pregnancy,
pubmed-meshheading:17187388-Pregnancy Trimester, First,
pubmed-meshheading:17187388-Serotonin Uptake Inhibitors
|
pubmed:year |
2007
|
pubmed:articleTitle |
First trimester exposure to paroxetine and risk of cardiac malformations in infants: the importance of dosage.
|
pubmed:affiliation |
Faculty of Pharmacy, University of Montreal, Montreal, Québec, Canada. anick.berard@umontreal.ca
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|