Source:http://linkedlifedata.com/resource/pubmed/id/17183628
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2006-12-20
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pubmed:abstractText |
Summary: Two phases of CD4+ T-cell increases are seen soon after potent antiretroviral therapy (ART) is initiated. In this 72-week analysis of 101 subjects with sustained viral suppression, we estimate the inflection point between the 2 phases to be 10 weeks after treatment initiation. Higher pretreatment HIV-1 RNA levels were associated with steeper initial CD4+ T-cell increases, likely reflecting greater redistribution of cells from lymphoid tissue to the peripheral blood compartment.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1525-4135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-5
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17183628-Anti-HIV Agents,
pubmed-meshheading:17183628-CD4 Lymphocyte Count,
pubmed-meshheading:17183628-Drug Therapy, Combination,
pubmed-meshheading:17183628-Female,
pubmed-meshheading:17183628-HIV Infections,
pubmed-meshheading:17183628-HIV-1,
pubmed-meshheading:17183628-Humans,
pubmed-meshheading:17183628-Male,
pubmed-meshheading:17183628-RNA, Viral,
pubmed-meshheading:17183628-Reverse Transcriptase Inhibitors,
pubmed-meshheading:17183628-Treatment Outcome,
pubmed-meshheading:17183628-Viral Load
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pubmed:year |
2006
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pubmed:articleTitle |
Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment.
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pubmed:affiliation |
Center for Biostatistics in AIDS Research, Harvard School of Public Health, 651 Huntington Avenue, Boston, MA 02115, USA. rbosch@hsph.harvard.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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