rdf:type |
|
lifeskim:mentions |
umls-concept:C0006556,
umls-concept:C0008643,
umls-concept:C0008651,
umls-concept:C0015576,
umls-concept:C0017337,
umls-concept:C0033684,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0679058,
umls-concept:C0680022,
umls-concept:C1172152,
umls-concept:C1516050,
umls-concept:C1547699,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C2700640
|
pubmed:issue |
8
|
pubmed:dateCreated |
1991-12-19
|
pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M75883,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M75884,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S59350,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S59352,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S59354,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S60919,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S60920,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S64702,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S64707,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X64572,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X64573,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X64574
|
pubmed:abstractText |
Sterol carrier protein 2 (SCP2) is believed to play a key role in intracellular lipid movement. Here we report the cloning and nucleotide sequences of cDNAs encoding SCP2-related proteins of 58.85 kD and 30.8 kD and the assignment of the SCP2 gene to human chromosome 1 p21-pter. The SCP2-related proteins share common deduced carboxyl amino acid sequences with SCP2 and the cDNAs have a common 3' untranslated nucleotide sequence. The mRNAs encoding these proteins increased in a coordinate fashion as human placental cytotrophoblasts differentiated into syncytiotrophoblasts in culture. Our observations document the existence of a family of related proteins encoded by the human SCP2 gene.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1044-5498
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
559-69
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:1718316-Amino Acid Sequence,
pubmed-meshheading:1718316-Base Sequence,
pubmed-meshheading:1718316-Blotting, Northern,
pubmed-meshheading:1718316-Carrier Proteins,
pubmed-meshheading:1718316-Cells, Cultured,
pubmed-meshheading:1718316-Chromosome Mapping,
pubmed-meshheading:1718316-Chromosomes, Human, Pair 1,
pubmed-meshheading:1718316-Cloning, Molecular,
pubmed-meshheading:1718316-DNA,
pubmed-meshheading:1718316-Humans,
pubmed-meshheading:1718316-Molecular Sequence Data,
pubmed-meshheading:1718316-Plant Proteins,
pubmed-meshheading:1718316-Poly A,
pubmed-meshheading:1718316-Polymerase Chain Reaction,
pubmed-meshheading:1718316-RNA,
pubmed-meshheading:1718316-RNA, Messenger,
pubmed-meshheading:1718316-Restriction Mapping,
pubmed-meshheading:1718316-Sterols
|
pubmed:year |
1991
|
pubmed:articleTitle |
cDNAs encoding members of a family of proteins related to human sterol carrier protein 2 and assignment of the gene to human chromosome 1 p21----pter.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia 19104.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|