Linked Life Data

17183151

Source:http://linkedlifedata.com/resource/pubmed/id/17183151

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-12-21
pubmed:abstractText
Treatment with HMG-CoA reductase inhibitors ("statins") has been variably associated with a reduced risk of Alzheimer's disease (AD) in epidemiologic studies and reduced amyloid-beta (Abeta) deposition in animal models of AD. Putative neuroprotective effects of statins may vary in relation to their ability to penetrate into the central nervous system (CNS).
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Peptides, http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Protein Precursor, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL, http://linkedlifedata.com/resource/pubmed/chemical/F2-Isoprostanes, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA..., http://linkedlifedata.com/resource/pubmed/chemical/Neuroprotective Agents, http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments, http://linkedlifedata.com/resource/pubmed/chemical/Pravastatin, http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin, http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides, http://linkedlifedata.com/resource/pubmed/chemical/amyloid beta-peptide (5-40), http://linkedlifedata.com/resource/pubmed/chemical/amyloid beta-protein (1-42), http://linkedlifedata.com/resource/pubmed/chemical/tau Proteins
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1387-2877
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-406
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:17183151-Adult, pubmed-meshheading:17183151-Aged, pubmed-meshheading:17183151-Aged, 80 and over, pubmed-meshheading:17183151-Alzheimer Disease, pubmed-meshheading:17183151-Amyloid beta-Peptides, pubmed-meshheading:17183151-Amyloid beta-Protein Precursor, pubmed-meshheading:17183151-Brain, pubmed-meshheading:17183151-Cholesterol, pubmed-meshheading:17183151-Cholesterol, LDL, pubmed-meshheading:17183151-F2-Isoprostanes, pubmed-meshheading:17183151-Female, pubmed-meshheading:17183151-Humans, pubmed-meshheading:17183151-Hydroxymethylglutaryl-CoA Reductase Inhibitors, pubmed-meshheading:17183151-Hypercholesterolemia, pubmed-meshheading:17183151-Male, pubmed-meshheading:17183151-Middle Aged, pubmed-meshheading:17183151-Neuroprotective Agents, pubmed-meshheading:17183151-Peptide Fragments, pubmed-meshheading:17183151-Pravastatin, pubmed-meshheading:17183151-Simvastatin, pubmed-meshheading:17183151-Triglycerides, pubmed-meshheading:17183151-tau Proteins
pubmed:year
2006
pubmed:articleTitle
Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.
pubmed:affiliation
Department of Medicine, Division of Geriatric Medicine, University of Washington School of Medicine, and VA Puget Sound Health Care System, Seattle, WA 98108, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural