|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2007-3-7
|
|
pubmed:abstractText |
The occurrence of multiple small pancreatic endocrine tumors in patients suffering from multiple endocrine neoplasia type 1 (MEN1) represents a unique possibility to study early neoplasms and their potential precursor lesions. To date, it is unknown whether small islet-like endocrine cell clusters found in MEN1 patients are neoplastic or rather hyperplastic. It is also unclear whether microadenomas develop from islets.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0021-972X
|
|
pubmed:author |
pubmed-author:AnlaufMartinM,
pubmed-author:DralleHenningH,
pubmed-author:GimmOliverO,
pubmed-author:HeitzPhilipp UPU,
pubmed-author:HenoppTobiasT,
pubmed-author:KlöppelGünterG,
pubmed-author:KnoefelWolfram TWT,
pubmed-author:KomminothPaulP,
pubmed-author:PerrenAurelA,
pubmed-author:RaffelAndreasA,
pubmed-author:RudolphThomasT,
pubmed-author:SchmittAnjaA,
pubmed-author:WeiheEberhardE
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
92
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1118-28
|
|
pubmed:meshHeading |
pubmed-meshheading:17179192-Adult,
pubmed-meshheading:17179192-Aged,
pubmed-meshheading:17179192-Carcinoma, Pancreatic Ductal,
pubmed-meshheading:17179192-Female,
pubmed-meshheading:17179192-Humans,
pubmed-meshheading:17179192-Hyperplasia,
pubmed-meshheading:17179192-Loss of Heterozygosity,
pubmed-meshheading:17179192-Male,
pubmed-meshheading:17179192-Middle Aged,
pubmed-meshheading:17179192-Models, Biological,
pubmed-meshheading:17179192-Multiple Endocrine Neoplasia Type 1,
pubmed-meshheading:17179192-Pancreas,
pubmed-meshheading:17179192-Pancreatic Neoplasms,
pubmed-meshheading:17179192-Proto-Oncogene Proteins
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Multiple endocrine neoplasia type 1 (MEN1): loss of one MEN1 allele in tumors and monohormonal endocrine cell clusters but not in islet hyperplasia of the pancreas.
|
|
pubmed:affiliation |
Institute of Surgical Pathology, Department of Pathology, University Hospital Zürich, 8091 Zürich, Switzerland. aurel.perren@usz.ch
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
