Source:http://linkedlifedata.com/resource/pubmed/id/17177409
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
51
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pubmed:dateCreated |
2006-12-20
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pubmed:abstractText |
Treatment of the eta9,eta5-bis(indenyl)zirconium sandwich complex, (eta9-C9H5-1,3-(SiMe3)2)(eta5-C9H5-1,3-(SiMe3)2)Zr, with dialkyl ethers such as diethyl ether, CH3OR (R=Et, nBu, tBu), nBu2O, or iPr2O resulted in facile C-O bond scission furnishing an eta5,eta5-bis(indenyl)zirconium alkoxy hydride complex and free olefin. In cases where ethylene is formed, trapping by the zirconocene sandwich yields a rare example of a crystallographically characterized, base-free eta5,eta5-bis(indenyl)zirconium ethylene complex. Observation of normal, primary kinetic isotope effects in combination with rate studies and the stability of various model compounds support a mechanism involving rate-determining C-H activation to yield an eta5,eta5-bis(indenyl)zirconium alkyl hydride intermediate followed by rapid beta-alkoxide elimination. For isolable eta6,eta5-bis(indenyl)zirconium THF compounds, thermolysis at 85 degrees C also resulted in C-O bond cleavage to yield the corresponding zirconacycle. Both mechanistic and computational studies again support a pathway involving haptotropic rearrangement to eta5,eta5-bis(indenyl)zirconium intermediates that promote rate-determining C-H activation and ultimately C-O bond scission.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carbon,
http://linkedlifedata.com/resource/pubmed/chemical/Esters,
http://linkedlifedata.com/resource/pubmed/chemical/Organometallic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/Zirconium
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-7863
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16600-12
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pubmed:meshHeading |
pubmed-meshheading:17177409-Carbon,
pubmed-meshheading:17177409-Esters,
pubmed-meshheading:17177409-Kinetics,
pubmed-meshheading:17177409-Magnetic Resonance Spectroscopy,
pubmed-meshheading:17177409-Models, Chemical,
pubmed-meshheading:17177409-Models, Molecular,
pubmed-meshheading:17177409-Molecular Conformation,
pubmed-meshheading:17177409-Organometallic Compounds,
pubmed-meshheading:17177409-Oxygen,
pubmed-meshheading:17177409-Sensitivity and Specificity,
pubmed-meshheading:17177409-Stereoisomerism,
pubmed-meshheading:17177409-Zirconium
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pubmed:year |
2006
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pubmed:articleTitle |
Carbon-oxygen bond cleavage with eta9,eta5-bis(indenyl)zirconium sandwich complexes.
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pubmed:affiliation |
Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14853, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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