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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-12-18
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pubmed:abstractText |
We report here two cases of patients with acute myeloblastic leukemia, type M1 (FAB classification), associated with a t(10;17)(p15;q21). Fluorescence in situ hybridization with the LSI PML/RARA dual-color probe showed the breakpoint to be distal to the RARA locus. Four other patients with this translocation have been reported, three of them having acute undifferentiated or poorly differentiated leukemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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|
pubmed:issn |
0165-4608
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
172
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
74-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17175384-Aged,
pubmed-meshheading:17175384-Chromosomes, Human, Pair 10,
pubmed-meshheading:17175384-Chromosomes, Human, Pair 17,
pubmed-meshheading:17175384-Humans,
pubmed-meshheading:17175384-In Situ Hybridization, Fluorescence,
pubmed-meshheading:17175384-Leukemia, Myeloid, Acute,
pubmed-meshheading:17175384-Male,
pubmed-meshheading:17175384-Neoplasm Proteins,
pubmed-meshheading:17175384-Neoplasm Recurrence, Local,
pubmed-meshheading:17175384-Nuclear Proteins,
pubmed-meshheading:17175384-Receptors, Retinoic Acid,
pubmed-meshheading:17175384-Transcription Factors,
pubmed-meshheading:17175384-Translocation, Genetic,
pubmed-meshheading:17175384-Tumor Suppressor Proteins
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pubmed:year |
2007
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pubmed:articleTitle |
Translocation (10;17)(p15;q21) is a recurrent anomaly in acute myeloblastic leukemia.
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pubmed:affiliation |
Department of Clinical Hematology, Institute of Cancerology and Hematology, CHU Morvan, Avenue Foch, 29609 Brest, France.
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pubmed:publicationType |
Journal Article,
Case Reports
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