Source:http://linkedlifedata.com/resource/pubmed/id/17173933
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2007-2-16
|
pubmed:abstractText |
In cardiopulmonary bypass, extracorporeal circulation activates neutrophils, which contribute to ischemia reperfusion injury and postoperative myocardial dysfunction. Perfluorocarbons (PFCs) are compounds that dissolve oxygen and have anti-inflammatory and neutrophil-stabilizing properties. We hypothesized that perflubron emulsion (PFE), a PFC, would attenuate neutrophil activation during simulated extracorporeal circulation (SECC) and would preserve myocardial functional recovery during reperfusion after cold ischemia.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0022-4804
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
138
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
135-40
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17173933-Animals,
pubmed-meshheading:17173933-Anti-Inflammatory Agents,
pubmed-meshheading:17173933-Cell Adhesion,
pubmed-meshheading:17173933-Cold Temperature,
pubmed-meshheading:17173933-Coronary Circulation,
pubmed-meshheading:17173933-Extracorporeal Circulation,
pubmed-meshheading:17173933-Fluorocarbons,
pubmed-meshheading:17173933-Heart,
pubmed-meshheading:17173933-Male,
pubmed-meshheading:17173933-Myocardium,
pubmed-meshheading:17173933-Neutrophils,
pubmed-meshheading:17173933-Perfusion,
pubmed-meshheading:17173933-Rats,
pubmed-meshheading:17173933-Rats, Sprague-Dawley,
pubmed-meshheading:17173933-Recovery of Function,
pubmed-meshheading:17173933-Reperfusion Injury
|
pubmed:year |
2007
|
pubmed:articleTitle |
Perflubron emulsion prevents PMN activation and improves myocardial functional recovery after cold ischemia and reperfusion.
|
pubmed:affiliation |
Department of Surgery, University of Texas Medical School at Houston, University of Texas Health Sciences Center at Houston, Houston, Texas 77030, USA . scgalemd@yahoo.com <scgalemd@yahoo.com>
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|