Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-1-15
pubmed:abstractText
We investigated the neural correlates of semantic priming by using event-related fMRI to record blood oxygen level dependent (BOLD) responses while participants performed speeded lexical decisions (word/nonword) on visually presented related versus unrelated prime-target pairs. A long stimulus onset asynchrony of 1000 ms was employed, which allowed for increased controlled processing and selective frequency-based ambiguity priming. Conditions included an ambiguous word prime (e.g. bank) and a target related to its dominant (e.g. money) or subordinate meaning (e.g. river). Compared to an unrelated condition, primed dominant targets were associated with increased activity in the LIFG, the right anterior cingulate and superior temporal gyrus, suggesting postlexical semantic integrative mechanisms, while increased right supramarginal activity for the unrelated condition was consistent with expectancy based priming. Subordinate targets were not primed and were associated with reduced activity primarily in occipitotemporal regions associated with word recognition, which may be consistent with frequency-based meaning suppression. These findings provide new insights into the neural substrates of semantic priming and the functional-anatomic correlates of lexical ambiguity suppression mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
1131
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-72
pubmed:meshHeading
pubmed-meshheading:17173868-Adult, pubmed-meshheading:17173868-Brain Mapping, pubmed-meshheading:17173868-Cerebral Cortex, pubmed-meshheading:17173868-Cerebrovascular Circulation, pubmed-meshheading:17173868-Evoked Potentials, pubmed-meshheading:17173868-Female, pubmed-meshheading:17173868-Functional Laterality, pubmed-meshheading:17173868-Gyrus Cinguli, pubmed-meshheading:17173868-Humans, pubmed-meshheading:17173868-Language, pubmed-meshheading:17173868-Language Tests, pubmed-meshheading:17173868-Magnetic Resonance Imaging, pubmed-meshheading:17173868-Male, pubmed-meshheading:17173868-Parietal Lobe, pubmed-meshheading:17173868-Pattern Recognition, Visual, pubmed-meshheading:17173868-Reaction Time, pubmed-meshheading:17173868-Reading, pubmed-meshheading:17173868-Semantics, pubmed-meshheading:17173868-Speech, pubmed-meshheading:17173868-Temporal Lobe, pubmed-meshheading:17173868-Verbal Behavior, pubmed-meshheading:17173868-Visual Cortex
pubmed:year
2007
pubmed:articleTitle
Neural correlates of semantic priming for ambiguous words: an event-related fMRI study.
pubmed:affiliation
Centre for Research in Language Processing and Linguistics, Division of Speech Pathology, The University of Queensland, St Lucia, QLD, 4072, Australia. d.copland@uq.edu.au
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't