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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1991-11-7
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pubmed:databankReference |
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pubmed:abstractText |
A cDNA encoding a 284 residue long type A/B hnRNP protein has been cloned. This protein, previously referred to as type C [(1987) J. Biol. Chem. 262, 17126-17137], is an RNA unwinding protein from HeLa 40S hnRNP with a high affinity for G- followed by U-rich sequences. The N-terminal part of the protein contains two consensus RNA binding domains present in a number of other RNA binding proteins. The C-terminal part is glycine-rich and contains a potential ATP/GTP binding loop. The distribution of charged amino acids is highly uneven and there are multiple potential phosphorylation sites.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
290
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-61
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1717314-Amino Acid Sequence,
pubmed-meshheading:1717314-Base Sequence,
pubmed-meshheading:1717314-Binding Sites,
pubmed-meshheading:1717314-Cloning, Molecular,
pubmed-meshheading:1717314-DNA,
pubmed-meshheading:1717314-HeLa Cells,
pubmed-meshheading:1717314-Heterogeneous-Nuclear Ribonucleoproteins,
pubmed-meshheading:1717314-Humans,
pubmed-meshheading:1717314-Molecular Sequence Data,
pubmed-meshheading:1717314-RNA,
pubmed-meshheading:1717314-Ribonucleoproteins
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pubmed:year |
1991
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pubmed:articleTitle |
Cloning and sequence analysis of a human type A/B hnRNP protein.
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pubmed:affiliation |
Department of Biochemistry, New York University School of Medicine, NY 10016.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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