|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
1991-11-8
|
|
pubmed:abstractText |
The serum of patients with myocarditis and dilated cardiomyopathy contains immunoglobulins capable of causing in vitro acceleration of beating of neonatal rat heart myocytes. This effect is stereoselectively inhibited by (-)-propranolol and is inhibited also by the beta 1-selective adrenergic antagonists, bisoprolol and metoprolol. This effect is not reversed by washing and continues unabated for at least 24 h.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0195-668X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
12 Suppl D
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
178-81
|
|
pubmed:dateRevised |
2005-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:1717272-Adrenergic beta-Antagonists,
pubmed-meshheading:1717272-Animals,
pubmed-meshheading:1717272-Autoantibodies,
pubmed-meshheading:1717272-Cardiomyopathy, Dilated,
pubmed-meshheading:1717272-Cells, Cultured,
pubmed-meshheading:1717272-Desensitization, Immunologic,
pubmed-meshheading:1717272-Heart Rate,
pubmed-meshheading:1717272-Humans,
pubmed-meshheading:1717272-Myocarditis,
pubmed-meshheading:1717272-Myocardium,
pubmed-meshheading:1717272-Rats,
pubmed-meshheading:1717272-Receptors, Adrenergic, beta,
pubmed-meshheading:1717272-gamma-Globulins
|
|
pubmed:year |
1991
|
|
pubmed:articleTitle |
Autoantibodies against the beta-adrenergic receptor in human myocarditis and dilated cardiomyopathy: beta-adrenergic agonism without desensitization.
|
|
pubmed:affiliation |
Institut für Herz-Kreislauf-Forschung, Berlin-Buch, Germany.
|
|
pubmed:publicationType |
Journal Article
|
