Linked Life Data

17168517

Source:http://linkedlifedata.com/resource/pubmed/id/17168517

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2006-12-15
pubmed:abstractText
The formation of amyloid assemblies is associated with major human disorders. Yet no therapeutic agents presently exist to control this process. In a recent paper, a new bacterial system is described that uses a fusion of the Alzheimer's disease beta-amyloid polypeptide to the GFP. The assay detects the formation of small, soluble amyloid intermediates associated with degenerative diseases. This assay allows the researchers to use high-throughput screening methods to find inhibitors of the formation of amyloid assemblies.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1554-8937
pubmed:author
pubmed:issnType
Electronic
pubmed:day
22
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
417-9
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
From green bacteria to human dementia: a novel model for discovering amyloid assembly inhibitors.
pubmed:affiliation
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv 69978, Israel. ehudg@post.tau.ac.il
pubmed:publicationType
Journal Article, Comment, Review