rdf:type |
|
lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0021469,
umls-concept:C0027627,
umls-concept:C0035647,
umls-concept:C0058372,
umls-concept:C0086418,
umls-concept:C0178595,
umls-concept:C0441712,
umls-concept:C1269955,
umls-concept:C1280500,
umls-concept:C1518174,
umls-concept:C2239176,
umls-concept:C2699153
|
pubmed:issue |
12
|
pubmed:dateCreated |
2006-12-14
|
pubmed:abstractText |
Invasion and metastasis is the main cause of the poor prognosis and high mortality of hepatocellular carcinoma (HCC). Inhibiting invasion and metastasis is an effective approach to reduce the development and mortality of HCC. Dimethyl dicarboxylate biphenyl (DDB) is an old anti-hepatitis drug used in clinics. This study was to assess the inhibitory effect of DDB on adhesion and invasion of HCC cell line MHCC97-H with high metastasis potential, and explore its possible mechanism.
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pubmed:language |
chi
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/7,7'-dimethoxy-(4,4'-bi-1,3-benzodio...,
http://linkedlifedata.com/resource/pubmed/chemical/Dioxoles,
http://linkedlifedata.com/resource/pubmed/chemical/NM23 Nucleoside Diphosphate Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/NME1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Urokinase Plasminogen...,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Fetoproteins
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
1000-467X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1464-9
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pubmed:meshHeading |
pubmed-meshheading:17166368-Carcinoma, Hepatocellular,
pubmed-meshheading:17166368-Cell Adhesion,
pubmed-meshheading:17166368-Cell Line, Tumor,
pubmed-meshheading:17166368-Dioxoles,
pubmed-meshheading:17166368-Humans,
pubmed-meshheading:17166368-NM23 Nucleoside Diphosphate Kinases,
pubmed-meshheading:17166368-Neoplasm Invasiveness,
pubmed-meshheading:17166368-Neoplasm Metastasis,
pubmed-meshheading:17166368-RNA, Messenger,
pubmed-meshheading:17166368-Receptors, Urokinase Plasminogen Activator,
pubmed-meshheading:17166368-Vascular Endothelial Growth Factor A,
pubmed-meshheading:17166368-alpha-Fetoproteins
|
pubmed:year |
2006
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pubmed:articleTitle |
[Inhibitory effect of dimethyl dicarboxylate biphenyl on invasion of human hepatocellular carcinoma cell line MHCC97-H with high metastasis potential and its mechanisms].
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pubmed:affiliation |
Department of Pharmacology, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, 100050, P. R. China.
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pubmed:publicationType |
Journal Article,
English Abstract
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