Linked Life Data

17163700

Source:http://linkedlifedata.com/resource/pubmed/id/17163700

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2006-12-13
pubmed:abstractText
Combining supramolecular self-assembly of lipids with enzymatic triggered DNA interfacial polymerization allows construction of composite nanocapsules. Covalent grafting of oligonucleotides functionalizes the surface of liposomes. Subsequent addition of an enzyme called terminal deoxynucleotidyl transferase elongates the single-stranded DNA. The elongated DNA hybridizes, creating a random network. The short segments of double-stranded DNA provides a substrate for the Klenow fragment of E. coli DNA polymerase, which synthesizes a double-strand DNA, reinforcing the network. Alternate action of both enzymes leads to a three-dimensional network anchored on the liposome surface.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1530-6984
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2755-7
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Stabilization of liposomes through enzymatic polymerization of DNA.
pubmed:affiliation
Institut Pharmacologie et Biologie Structurale, UMR CNRS Université Paul Sabatier, 5089 Toulouse, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't