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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-10-4
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pubmed:abstractText |
We have studied the prevalence of antibody against hepatitis C virus (anti-HCV) and its relation to the time of onset of the symptoms in 57 patients with acute non-A, non-B hepatitis: 16 post-transfusion, 25 drug addicts and 16 sporadic cases. In the 1st month after the onset of illness, anti-HCV was positive in 25% of patients with post-transfusion hepatitis, 44% of drug addicts and 25% of sporadic hepatitis. In the 3rd month this antibody was detected in 75%, 88% and 31.2%, and in the 6th month in 87.5%, 96% and 31.2%, respectively. The prevalence in the 3rd and 6th months was significantly higher in post-transfusion patients and drug addicts than in sporadic cases. In the 6th month the prevalence of anti-HCV in patients who progressed towards chronicity was also significantly higher than in those with acute resolving non-A, non-B hepatitis (94% vs 50%, p less than 0.001). These results show that HCV is probably the main agent in acute post-transfusion non-A, non-B hepatitis and in those occurring in drug addicts, and that in a high proportion of these patients the anti-HCV can be detected in the 3rd month after the beginning of the symptoms. On the other hand, the relation of hepatitis C virus with sporadic acute non-A, non-B hepatitis may be doubtful.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0106-9543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-33
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1715963-Acute Disease,
pubmed-meshheading:1715963-Adult,
pubmed-meshheading:1715963-Blood Transfusion,
pubmed-meshheading:1715963-Female,
pubmed-meshheading:1715963-Hepacivirus,
pubmed-meshheading:1715963-Hepatitis Antibodies,
pubmed-meshheading:1715963-Hepatitis C,
pubmed-meshheading:1715963-Hepatitis C Antibodies,
pubmed-meshheading:1715963-Humans,
pubmed-meshheading:1715963-Male,
pubmed-meshheading:1715963-Middle Aged,
pubmed-meshheading:1715963-Prospective Studies,
pubmed-meshheading:1715963-Substance-Related Disorders
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pubmed:year |
1991
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pubmed:articleTitle |
Prevalence of antibody to hepatitis C virus in prospectively followed acute non-A, non-B hepatitis, from different epidemiological categories.
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pubmed:affiliation |
Gastroenterology Unit, Covadonga Hospital, Oviedo, Spain.
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pubmed:publicationType |
Journal Article
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