rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-12-12
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pubmed:abstractText |
Fabry disease results in a global vasculopathy leading to early-onset stroke and renal and cardiac failure. We found that random myeloperoxidase in serum and plasma was significantly elevated in 73 consecutive male patients with Fabry disease. Random serum myeloperoxidase level in men predicted the risk of a Fabry vasculopathy-related event in subsequent years. Long-term enzyme replacement therapy did not reduce myeloperoxidase level or eliminate the risk of vasculopathic events.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1526-632X
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2045-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17159117-Adolescent,
pubmed-meshheading:17159117-Adult,
pubmed-meshheading:17159117-Aged,
pubmed-meshheading:17159117-Aged, 80 and over,
pubmed-meshheading:17159117-Cardiovascular Diseases,
pubmed-meshheading:17159117-Child,
pubmed-meshheading:17159117-Fabry Disease,
pubmed-meshheading:17159117-Female,
pubmed-meshheading:17159117-Follow-Up Studies,
pubmed-meshheading:17159117-Humans,
pubmed-meshheading:17159117-Male,
pubmed-meshheading:17159117-Middle Aged,
pubmed-meshheading:17159117-Peroxidase,
pubmed-meshheading:17159117-Predictive Value of Tests,
pubmed-meshheading:17159117-Prospective Studies,
pubmed-meshheading:17159117-Risk Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Myeloperoxidase predicts risk of vasculopathic events in hemizgygous males with Fabry disease.
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pubmed:affiliation |
Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke National Institutes of Health, Bethesda, MD 20892-1260, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Intramural
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