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pubmed-article:17157947pubmed:abstractTextHepatic oxidative stress is a key feature of metabolic forms of steatohepatitis, but the sources of pro-oxidants are unclear. The NADPH oxidase complex is critical for ROS generation in inflammatory cells; loss of any one component (e.g., gp91phox) renders NADPH oxidase inactive. We tested whether activated inflammatory cells contribute to oxidant stress in steatohepatitis.lld:pubmed
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pubmed-article:17157947pubmed:articleTitleNADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.lld:pubmed
pubmed-article:17157947pubmed:affiliationStorr Liver Unit, Westmead Millennium Institute, University of Sydney at Westmead Hospital, NSW, Australia.lld:pubmed
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pubmed-article:17157947pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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