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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-12-25
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pubmed:abstractText |
Hepatic oxidative stress is a key feature of metabolic forms of steatohepatitis, but the sources of pro-oxidants are unclear. The NADPH oxidase complex is critical for ROS generation in inflammatory cells; loss of any one component (e.g., gp91phox) renders NADPH oxidase inactive. We tested whether activated inflammatory cells contribute to oxidant stress in steatohepatitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL4,
http://linkedlifedata.com/resource/pubmed/chemical/Choline,
http://linkedlifedata.com/resource/pubmed/chemical/Cybb protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Adhesion Molecule-1,
http://linkedlifedata.com/resource/pubmed/chemical/Macrophage Inflammatory Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Methionine,
http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
304-13
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17157947-Animals,
pubmed-meshheading:17157947-Chemokine CCL2,
pubmed-meshheading:17157947-Chemokine CCL4,
pubmed-meshheading:17157947-Choline,
pubmed-meshheading:17157947-Choline Deficiency,
pubmed-meshheading:17157947-Cyclooxygenase 2,
pubmed-meshheading:17157947-Diet,
pubmed-meshheading:17157947-Disease Models, Animal,
pubmed-meshheading:17157947-Fatty Liver,
pubmed-meshheading:17157947-Female,
pubmed-meshheading:17157947-Gene Expression Regulation,
pubmed-meshheading:17157947-Hepatitis,
pubmed-meshheading:17157947-Intercellular Adhesion Molecule-1,
pubmed-meshheading:17157947-Liver,
pubmed-meshheading:17157947-Macrophage Inflammatory Proteins,
pubmed-meshheading:17157947-Membrane Glycoproteins,
pubmed-meshheading:17157947-Methionine,
pubmed-meshheading:17157947-Mice,
pubmed-meshheading:17157947-Mice, Mutant Strains,
pubmed-meshheading:17157947-NADPH Oxidase,
pubmed-meshheading:17157947-NF-kappa B,
pubmed-meshheading:17157947-Oxidative Stress,
pubmed-meshheading:17157947-RNA, Messenger,
pubmed-meshheading:17157947-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.
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pubmed:affiliation |
Storr Liver Unit, Westmead Millennium Institute, University of Sydney at Westmead Hospital, NSW, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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