rdf:type |
|
lifeskim:mentions |
umls-concept:C0035647,
umls-concept:C0039194,
umls-concept:C0086418,
umls-concept:C0205225,
umls-concept:C0205263,
umls-concept:C0205410,
umls-concept:C0332157,
umls-concept:C0442805,
umls-concept:C0882849,
umls-concept:C1155013,
umls-concept:C1749388,
umls-concept:C2728259
|
pubmed:issue |
12
|
pubmed:dateCreated |
2006-12-12
|
pubmed:abstractText |
The Notch pathway plays a key role in cell fate choices and in T-cell development. The goal of our study was to evaluate whether a short in vitro stimulation of the Notch pathway may alter human progenitor cell behavior.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0301-472X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1720-9
|
pubmed:meshHeading |
pubmed-meshheading:17157169-Antigens, CD34,
pubmed-meshheading:17157169-B-Lymphocytes,
pubmed-meshheading:17157169-Cell Differentiation,
pubmed-meshheading:17157169-Cells, Cultured,
pubmed-meshheading:17157169-Hematopoietic Stem Cells,
pubmed-meshheading:17157169-Humans,
pubmed-meshheading:17157169-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:17157169-Signal Transduction,
pubmed-meshheading:17157169-T-Lymphocytes
|
pubmed:year |
2006
|
pubmed:articleTitle |
Short exposure to Notch ligand Delta-4 is sufficient to induce T-cell differentiation program and to increase the T cell potential of primary human CD34+ cells.
|
pubmed:affiliation |
Inserm U 421, Faculté de Médecine, Créteil, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|