|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2006-12-12
|
|
pubmed:abstractText |
Reactive oxygen species (ROS), generated following benzene exposure, are considered to trigger the development of hematopoietic neoplasms, although little supporting evidence has been found. In this study, we examined whether the experimental elimination of ROS generated following benzene exposure prevents the development of benzene-induced hematopoietic disorders to clarify the mechanism underlying the development of benzene-induced hematopoietic disorders.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1687-97
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:17157166-Animals,
pubmed-meshheading:17157166-Benzene,
pubmed-meshheading:17157166-Burkitt Lymphoma,
pubmed-meshheading:17157166-Carcinogens,
pubmed-meshheading:17157166-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:17157166-Cytochrome P-450 CYP2E1,
pubmed-meshheading:17157166-Down-Regulation,
pubmed-meshheading:17157166-Genotype,
pubmed-meshheading:17157166-Hematologic Diseases,
pubmed-meshheading:17157166-Humans,
pubmed-meshheading:17157166-Immunity, Innate,
pubmed-meshheading:17157166-Mice,
pubmed-meshheading:17157166-Mice, Inbred C57BL,
pubmed-meshheading:17157166-Mice, Transgenic,
pubmed-meshheading:17157166-Models, Animal,
pubmed-meshheading:17157166-Oxidative Stress,
pubmed-meshheading:17157166-RNA, Messenger,
pubmed-meshheading:17157166-Reactive Oxygen Species,
pubmed-meshheading:17157166-Receptors, Aryl Hydrocarbon,
pubmed-meshheading:17157166-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17157166-Survival Rate,
pubmed-meshheading:17157166-Thioredoxins,
pubmed-meshheading:17157166-Thymus Gland
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Thioredoxin overexpression in mice, model of attenuation of oxidative stress, prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.
|
|
pubmed:affiliation |
Division of Cellular and Molecular Toxicology, Biological Safety and Research Center, National Institute of Health Sciences, Tokyo, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
