Source:http://linkedlifedata.com/resource/pubmed/id/17156897
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2007-2-9
|
| pubmed:abstractText |
Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents. Four of the compounds described were found to have MICs<or=4 microg/mL against marker strains of Streptococcus pneumoniae and Staphylococcus aureus.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0223-5234
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
42
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
109-13
|
| pubmed:meshHeading |
pubmed-meshheading:17156897-Anti-Bacterial Agents,
pubmed-meshheading:17156897-Diterpenes,
pubmed-meshheading:17156897-Microbial Sensitivity Tests,
pubmed-meshheading:17156897-Staphylococcus aureus,
pubmed-meshheading:17156897-Streptococcus pneumoniae,
pubmed-meshheading:17156897-Structure-Activity Relationship
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Cyclopentanone ring-cleaved pleuromutilin derivatives.
|
| pubmed:affiliation |
Anti-infective Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, P.O. Box 5100, Wallingford, CT 06492, USA. springd@wyeth.com <springd@wyeth.com>
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| pubmed:publicationType |
Journal Article
|