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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-2-21
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pubmed:abstractText |
A significant association between the DLG5 variant (R30Q) and inflammatory bowel disease (IBD) has been confirmed in several independent adult IBD cohorts. There is growing evidence that gender significantly influences R30Q susceptibility in Crohn's disease (CD). Pediatric onset CD features a significantly lower incidence for female children compared with male children. We, therefore, studied the influence of gender on R30Q susceptibility in an exclusively pediatric onset IBD cohort.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9270
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
391-8
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17156146-Age of Onset,
pubmed-meshheading:17156146-Child,
pubmed-meshheading:17156146-Crohn Disease,
pubmed-meshheading:17156146-DNA,
pubmed-meshheading:17156146-Female,
pubmed-meshheading:17156146-Gene Frequency,
pubmed-meshheading:17156146-Genetic Predisposition to Disease,
pubmed-meshheading:17156146-Genotype,
pubmed-meshheading:17156146-Humans,
pubmed-meshheading:17156146-Incidence,
pubmed-meshheading:17156146-Infant, Newborn,
pubmed-meshheading:17156146-Male,
pubmed-meshheading:17156146-Membrane Proteins,
pubmed-meshheading:17156146-Polymerase Chain Reaction,
pubmed-meshheading:17156146-Prognosis,
pubmed-meshheading:17156146-Retrospective Studies,
pubmed-meshheading:17156146-Sex Factors,
pubmed-meshheading:17156146-Tumor Suppressor Proteins
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pubmed:year |
2007
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pubmed:articleTitle |
DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease.
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pubmed:affiliation |
Department of Pediatrics, Medical College Wisconsin, Milwaukee, Wisconsin 53226, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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