Linked Life Data

17155720

Source:http://linkedlifedata.com/resource/pubmed/id/17155720

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2006-12-12
pubmed:abstractText
Using a theoretical model for spontaneous partial DNA unwrapping from histones, we study the transient exposure of protein-binding DNA sites within nucleosomes. We focus on the functional dependence of the rates for site exposure and reburial on the site position, which is measurable experimentally and pertinent to gene regulation. We find the dependence to be roughly described by a random walker model. Close inspection reveals a surprising physical effect of flexibility-assisted barrier crossing, which we characterize within a toy model, the "semiflexible Brownian rotor."
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0031-9007
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
208102
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Kinetic accessibility of buried DNA sites in nucleosomes.
pubmed:affiliation
Arnold Sommerfeld Center for Theoretical Physics and Center for Nanoscience, LMU München, Theresienstrasse 37, 80333 München, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't