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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1991-10-1
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pubmed:abstractText |
The aim of this study was to assess the behavior of the diastolic left ventricular (LV) filling pattern and cardiac hypertrophy after treatment with cilazapril. Twelve patients (9 male and 3 female) with mild to moderate essential hypertension, aged 46 +/- 14.1 years, were treated with cilazapril for 1 year. They underwent Doppler echocardiography at the beginning (I), after 6 months (II), and after 1 year (III) of treatment. The following parameters were evaluated: mean arterial pressure (MAP) automatically recorded for 24 h, interventricular septal and posterior wall thickness, LV and end-diastolic diameter, LV mass index, early (E) and late (A) diastolic filling flow velocities, and the ratio E/A. A significant reduction in LV hypertrophy and an improved diastolic filling pattern of the left ventricle was shown after 6 months of therapy with cilazapril; this improvement still remained after 1 year of therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0160-2446
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S159-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1715471-Adult,
pubmed-meshheading:1715471-Aged,
pubmed-meshheading:1715471-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:1715471-Blood Pressure,
pubmed-meshheading:1715471-Cardiomegaly,
pubmed-meshheading:1715471-Cilazapril,
pubmed-meshheading:1715471-Echocardiography, Doppler,
pubmed-meshheading:1715471-Female,
pubmed-meshheading:1715471-Heart Rate,
pubmed-meshheading:1715471-Humans,
pubmed-meshheading:1715471-Hypertension,
pubmed-meshheading:1715471-Male,
pubmed-meshheading:1715471-Middle Aged,
pubmed-meshheading:1715471-Pyridazines,
pubmed-meshheading:1715471-Ventricular Function
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pubmed:year |
1991
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pubmed:articleTitle |
Improvement of diastolic filling in hypertensive patients treated with cilazapril.
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pubmed:affiliation |
University Hospital, Giessen, F.R.G.
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pubmed:publicationType |
Journal Article
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