Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12 Pt 2
pubmed:dateCreated
2006-12-7
pubmed:abstractText
In this letter, we consider how to combine neuronal signals from multiple electrodes to optimally predict behavioral choices from observed neural activity. The predictability is often quantified by the area under the receiver operating characteristic (ROC) curve, also called choice probability (CP) in neurophysiology. We exploit a distribution-free relaxation based multichannel signal combination (RELAX-MUSIC) approach that requires only simple pairwise combination and recursive implementation for optimizing the area under the ROC curve. A permutation test is employed to assess the statistical significance of the derived CP. We demonstrate that the RELAX-MUSIC approach outperforms the commonly used response pooling and Fisher linear discriminant (FLD) methods. The excellent performances of the RELAX-MUSIC approach for predicting perceptual decisions from neural activity are demonstrated via examples using simulated and experimental data.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0018-9294
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2615-8
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Relaxation-based multichannel signal combination (RELAX-MUSIC) for ROC analysis of percept-related neuronal activity.
pubmed:affiliation
School of Health Information Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural