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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-9-20
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pubmed:abstractText |
The proliferative activity of 21 cases of renal cell carcinoma has been investigated by means of monoclonal antibody Ki-67 and Nucleolar Organizer Regions (AgNORs) analysis. The correlation between AgNOR counts and Ki-67 scores was only slightly significant (r = 0.53, r2 = 0.28) as determined by linear regression. Positive correlation was found between Ki-67 scores and tumour histologic grade. However, no correlation was observed between Ki-67 scores and tumour pathologic stage and between AgNOR counts and tumour histologic grade and/or pathologic stage. The results suggest that AgNOR counts cannot replace Ki-67 scores in evaluating the proliferative activity of renal cell carcinoma and that such activity and both histologic grade and pathologic stage seem to be independent parametres.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0344-0338
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
187
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
482-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1715079-Analysis of Variance,
pubmed-meshheading:1715079-Antibodies, Monoclonal,
pubmed-meshheading:1715079-Carcinoma, Renal Cell,
pubmed-meshheading:1715079-Humans,
pubmed-meshheading:1715079-Immunoenzyme Techniques,
pubmed-meshheading:1715079-Ki-67 Antigen,
pubmed-meshheading:1715079-Kidney Neoplasms,
pubmed-meshheading:1715079-Neoplasm Staging,
pubmed-meshheading:1715079-Nuclear Proteins,
pubmed-meshheading:1715079-Nucleolus Organizer Region,
pubmed-meshheading:1715079-Regression Analysis,
pubmed-meshheading:1715079-Silver,
pubmed-meshheading:1715079-Staining and Labeling
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pubmed:year |
1991
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pubmed:articleTitle |
Argyrophilic nucleolar organizer region counts and Ki-67 scores in human renal cell carcinoma.
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pubmed:affiliation |
Department of Biomedical Sciences and Human Oncology, University of Turin, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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